Modelling tectonic deformation along the North-Anatolian Fault in the Sea of Marmara

Using analogue techniques, we attempted to model the complex tectonic deformation pattern observed along the North-Anatolian Fault in the Sea of Marmara from morpho-bathymetry and seismic reflection images. In particular this paper focuses on the so-called Cinarcik segment of the fault connecting the eastern Izmit segment, which entirely ruptured during the Mw 7.4, 1999 earthquake, to the western segment of the Central High. The Çınarcık segment, potentially loaded after the Izmit earthquake, is expected to rupture during an earthquake occurring in the near future, possibly the next decades, with a high potential to affect the Istanbul metropolitan area. Our analysis suggests that the development of the observed structures accommodating strike-slip, transtensional and transpressional deformations, could be explained by changes in the geometry of fault segments within a right-lateral strike-slip tectonic regime. Tectonic deformations were reproduced in the analogue model by imposing a small (about 10°) and sharp difference in the relative orientations of the strike-slip segments at the edges of a major releasing bend. In the model slower strain accumulation occurs along the analogue of the Çınarcık segment than along the analogue of the Izmit segment of the fault. This would predict a delay for earthquakes triggered by stress transfer between the Izmit and Çınarcık segments. The model further predicts that most of the deformation in the Çınarcık basin is controlled by the sharp changes in the geometry of the fault itself

Fluid history related to the early Eocene-middle Miocene convergent system of the Northern Apennines (Italy). Constraints from structural and isotopic studies

The late Eocene-middle Miocene erosive plate boundary between the European and the Adriatic plates is exhumed in the Northem Apennines of Italy. The fossil fault zone is 500 m thick and the outcropping portion exposes the :first 5 km of its depth. At this plate boundary basai and frontal tectonic erosion incorporated unlithified, fluid-rich sediments into the fault zone. The deformation and nature of the material along the plate boundary define a fossil subduction channel. Here we couple a detailed structural analysis of the Apennine subduction channel, focusing, in particular, on calcite veins, with a stable isotope analysis to characterize the fluid regime along an active subduction channel. The 13C and 180 composition of calcite vein and host rock samples within the fault zone indicates that there is a deep metamorphic source of fluids migrating upward along the subduction channel, in addition to locally derived fluid components. Dewatering of subducting turbidites contributes significantly only in the shallowest part of the channel. Structural observations indicate fluid flow along and across the subduction channel. At deep levels fluid flow is associated with discrete deformation events on shear faults offset by dilational jogs :filled with implosion breccias. At intennediate levels deformation is stili cyclic and associated with repeated crack-and-seal events. At the shallowest levels deformation occurred, while portions of the subducting material were stili unlithi:fied. Here the deformation was quasicontinuous, without associated vein development. Both isotope and structural analyses indicate that this erosive subduction channel behaved as a weak: fault with a vertical maximum principal stres

Analysis and verification of ECA rules in intelligent environments

Intelligent Environments (IEs) are physical spaces where Information Technology (IT) and other pervasive computing technologies are combined in order to achieve specific goals for the users and the environment. IEs have the goal of enriching user experience, increasing awareness of the environment. A number of applications are currently being deployed in domains ranging from smart homes to e-health and autonomous vehicles. Quite often IE support human activities, thus essential requirements to be ensured are correctness, reliability, safety and security. In this paper we present how a set of techniques and tools that have been developed for the verification of software can be employed in the verification of IE described by means of event-condition-action rules. More precisely, we reduce the problem of verifying key properties of these rules to satisfiability and termination problems that can be addressed using state-of-the-art Satisfiability Modulo Theory (SMT) solvers and program analysers. Our approach has been implemented in a tool called vIRONy. Our approach has been validated on a number of case studies from the literature

Symbolic verification of event–condition–action rules in intelligent environments

In this paper we show how state-of-the art SMT-based techniques for software verification can be employed in the verification of event–condition–action rules in intelligent environments. Moreover, we exploit the specific features of intelligent environments to optimise the verification process. We compare our approach with previous work in a detailed evaluation section, showing how it improves both performance and expressivity of the language for event–condition–action rules

STAT1 activation in association with JAK2 exon 12 mutations

La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder individual y colectivo que impactan en la vida de las personas y conforman la identidad del poder judicial como un actor imprescindible en la construcción de un Estado democrático de derecho” (Suprema Corte de Justicia de la Nación, 2013:7). La incorporación de la perspectiva de género viene a garantizar la igualdad de posiciones (Kessler, 2014) entre mujeres y varones como una meta, trascendiendo la mera igualdad de oportunidades que hasta el presente se ha demostrado insuficiente para que las mujeres consigamos una ciudadanía plena. Al momento de incorporar la perspectiva de género en las sentencias, quienes juzgan deben tener presente en primer lugar, el impacto diferenciado de las normas en base al sexo de las personas. En segundo lugar, la interpretación y aplicación de las leyes en relación con (y en base a) estereotipos de género. Si, por ejemplo, quienes imparten justicia no tienen presentes los estereotipos de género vigentes detrás de las violaciones a los derechos humanos de las mujeres, si no los detectan ni cuestionan, entonces los reproducen. Tal como sostiene Scott (1996) el género es una categoría imprescindible para el análisis social. En tercer lugar, al momento del juzgamiento, se deben tener en cuenta las exclusiones legitimadas por la ley por pensar el mundo en términos binarios y androcéntricos; en cuarto lugar, la distribución no equitativa de recursos y poder que opera entre varones y mujeres en el marco de una organización social patriarcal, y, por último, el trato diferenciado por género legitimado por las propias leyes.Eje 3: Tramas violentas y espacios de exclusión.Instituto de Cultura Jurídic

Late Cenozoic tephrostratigraphy offshore the southern Central American Volcanic Arc: 2. Implications for magma production rates and subduction erosion

Pacific drill sites offshore Central America provide the unique opportunity to study the evolution of large explosive volcanism and the geotectonic evolution of the continental margin back into the Neogene. The temporal distribution of tephra layers established by tephrochonostratigraphy in Part 1 indicates a nearly continuous highly explosive eruption record for the Costa Rican and the Nicaraguan volcanic arc within the last 8 M.y. The widely distributed marine tephra layers comprise the major fraction of the respective erupted tephra volumes and masses thus providing insights into regional and temporal variations of large-magnitude explosive eruptions along the southern Central American Volcanic Arc (CAVA). We observe three pulses of enhanced explosive magmatism between 0-1 Ma at the Cordillera Central, between 1-2 Ma at the Guanacaste and at >3 Ma at the Western Nicaragua segments. Averaged over the long-term the minimum erupted magma flux (per unit arc length) is ∼0.017 g/ms. Tephra ages, constrained by Ar-Ar dating and by correlation with dated terrestrial tephras, yield time-variable accumulation rates of the intercalated pelagic sediments with four prominent phases of peak sedimentation rates that relate to tectonic processes of subduction erosion. The peak rate at >2.3 Ma near Osa particularly relates to initial Cocos Ridge subduction which began at 2.91±0.23 Ma as inferred by the 1.5 M.y. delayed appearance of the OIB geochemical signal in tephras from Barva volcano at 1.42 Ma. Subsequent tectonic re-arrangements probably involved crustal extension on the Guanacaste segment that favored the 2-1 Ma period of unusually massive rhyolite production

Inner and Outer Portions of Colonic Circular Muscle: Ultrastructural and Immunohistochemical Changes in Rat Chronically Treated with Otilonium Bromide

Rat colonic circular muscle, main target of otilonium bromide (OB) spasmolytic activity, is subdivided in an inner and outer portion. Since the inner one is particularly rich in organelles involved in calcium availability (caveolae, smooth endoplasmic reticulum, mitochondria), the expression of specific markers (Caveolin-1, eNOS, calreticulin, calsequestrin) in comparison with the outer portion was investigated. The possible changes of these organelles and related markers, and of muscarinic receptors (Mr2) were then studied after OB chronic exposition. Rats were treated with 2-20 mg/kg/OB for 10 or 30 days. Proximal colon was processed by electron microscopy, immunohistochemistry, and western blot. In colon strips the stimulated contractility response to muscarinic agonist was investigated. The inner portion showed a higher expression of Caveolin-1 and Mr2, but not of eNOS, calreticulin and calsequestrin, compared to the outer portion. Chronic OB treatment caused similar ultrastructural and immunohistochemical changes in both portions. Organelles and some related markers were increased at 10 days; Mr2 expression and muscle contractility induced by methacholine was increased at 30 days. The present findings: 1) provide new information on the immunohistochemical properties of the inner portion of the circular layer that are in favour of a role it might play in colonic motility distinct from that of the outer portion; 2) demonstrate that chronically administered OB interferes with cell structures and molecules responsible for calcium handling and storage, and modifies cholinergic transmission. In conclusion, chronic OB administration in the colonic circular muscle layer directly interacts with the organelles and molecules calcium-related and with the Mr2

Semen analysis of G olden R etriever healthy dogs and those affected by muscular dystrophy

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106077/1/and12079.pd